PUBLICATIONS

2024

DFT-guided Development of New Hemilabile (P^N) Ligands for Gold-(I/III) RedOx Catalysis : Application to the Thiotosylation of Aryl Iodides

Karim Muratov, Emil Zaripov, Maxim V. Berezovski and Fabien Gagosz* J. Am. Chem. Soc. 2024, 146, 3660–3674.

Preprint: https://doi.org/10.26434/chemrxiv-2023-s9w9p

Synthesis of a CF3-substituted 1,3,4-oxadiazoline and its use in the generation and trapping of an a-trifluoromethyl carbene

David F. León Rayo, Laurie-Anne Jouanno, and Fabien Gagosz Arkivoc 2024, Arkivoc 2024 (2) 202312164.

Special issue in honor of Prof. Samir Zard

2023

Copper and Silver Catalysis in the (3+2) Cycloaddition of Neutral Three-Atom Components with Terminal Alkynes

Dominic Campeau, Alice Pommainville, Mila Gorodnichy and Fabien Gagosz* J. Am. Chem. Soc. 2023, 145, 19018-19029.

Preprint: https://doi.org/10.26434/chemrxiv-2023-s9w9p

2022

Heteroatom-substituted alkynes as three-atom components in (3+2) cycloadditions

Dominic Campeau* and Fabien Gagosz* Cell Rep. Phys. Sci. 2022, 101212.

Steric, Electronic and Conformational Synergistic Effects in the Gold(I)-catalyzed α-C-H Bond Functionalization of Tertiary Amines


Selected as a hot paper

David F. León Rayo, Ali Mansour, Wenbin Wu, Benjamin N. Bhawal and Fabien Gagosz*. Angew. Chem. Int. Ed. 2022, e202212893.

Preprint: https://doi.org/10.26434/chemrxiv-2022-l2mlb

Confinement-Induced Selectivities in Gold(I) Catalysis–The Benefit of Using Bulky Tri-(ortho-biaryl)phosphine Ligands


Selected as a hot paper

Karim Muratov and Fabien Gagosz*. Angew. Chem. Int. Ed. 2022, 61, e202203452.

The Synthetic Potential of Thiophenium Ylide Cycloadducts


Selected as a hot paper

Alice Pommainville, Dominic Campeau, and Fabien Gagosz*. Angew. Chem. Int. Ed. 2022, 61, e202205963.

Preprint: https://doi.org/10.26434/chemrxiv-2022-61krg-v2

Asymmetric Total Synthesis of Antibiotic Elansolid A

Liang-Liang Wang*, Qi Yu, Wenjing Zhang, Shuai Yang, Lin Peng, Liang Zhang, Xiao-Nian Li, Fabien Gagosz, and Andreas Kirschning*. J. Am. Chem. Soc. 2022, 144, 6871–6881.

2021

Enantioselective access to tricyclic tetrahydropyran derivatives by a remote hydrogen bonding mediated intramolecular IEDHDA reaction

Min Jin, Congyun Tang, Shuai Yang, Ying-Tao Yang, Lin Peng, Xiao-Nian Li, Wenjing Zhang*, Zhili Zuo*, Fabien Gagosz, and Liang-Liang Wang*. Nat. Commun. 2021, 12, 7188–7195

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Ynamides as Three-Atom Components in Cycloadditions: An Unexplored Chemical Reaction Space

Dominic Campeau*, Alice Pommainville, and Fabien Gagosz*. J. Am. Chem. Soc. 2021, 143, 9601–9611

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On the mechanism of Au-catalyzed Enynamide-Yne Dehydro-Diels-Alder Reactions: An Experimental and Computational Study

David F. León Rayo, Young J. Hong, Dominic Campeau, Dean J. Tantillo*, and Fabien Gagosz*. Chem. Eur. J. 2021, 27, 10637–10648

2020

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Gold-Catalyzed Reactions of Specially Activated Alkynes, Allenes, and Alkenes

Dominic Campeau, David F. León Rayo, Ali Mansour, Karim Muratov, and Fabien Gagosz*. Chem. Rev. 2020, 121, 8756–8867

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Diastereoselective hydroalkylation of aryl alkenes enabled by remote hydride transfer

Dhika Aditya Gandamana, Fabien Gagosz*, and Shunsuke Chiba*. Tetrahedron 2020, 76, 131272

2019

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Diastereoselective Intramolecular Hydride Transfer Triggered by Electrophilic Halogenation of Aryl Alkenes

Bin Wang, Dhika Aditya Gandamana, David F. León Rayo, Fabien Gagosz*, and Shunsuke Chiba*. Org. Lett. 2019, 21, 9179–9182

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Diastereoselective Intramolecular Hydride Transfer Under Brønsted Acid Catalysis


ACS Editors’ Choice Article

Bin Wang, Dhika Aditya Gandamana, Fabien Gagosz*, and Shunsuke Chiba*. Org. Lett. 2019, 21, 2298–2301

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Gold Vinylidenes as Useful Intermediates in Synthetic Organic Chemistry


Invited article as part of the 50 Years SYNTHESIS - Golden Anniversary Issue

Fabien Gagosz*. Synthesis 2019, 51, 1087–1099

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Synthesis of isochroman-4-ones and 2H-pyran-3(6H)-ones by gold-catalyzed oxidative cycloalkoxylation of alkynes


Invited article as part of the special issue: “From controlling chemical bonding to deciphering and manipulating biological processes”

Qing Zhao, Guilhem Henrion, and Fabien Gagosz*. Bioorg. Med. Chem. 2019, 27, 2616–2620

2018

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Gold-Catalyzed Formal Dehydro-Diels-Alder Reactions of Ene-Ynamide Derivatives Bearing Terminal Alkyne Chains: Scope and Mechanistic Studies

Qing Zhao, David F. León Rayo, Dominic Campeau, Martin Daenen, and Fabien Gagosz*. Angew. Chem. Int. Ed. 2018, 57, 13603–13607

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Alkyl Ethers as Traceless Hydride Donors in Brønsted Acid Catalyzed Intramolecular Hydrogen Atom Transfer

Dhika Aditya Gandamana, Bin Wang, Ciputra Tejo, Benoit Bolte, Fabien Gagosz*, and Shunsuke Chiba*. Angew. Chem. Int. Ed. 2018, 57, 6181–6185

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Use of a benzyl ether as a traceless hydrogen donor in the anti-Markovnikov hydrofunctionalization of alkenes with xanthates

Hirohito Hayashi, Atsushi Kaga, Bin Wang, Fabien Gagosz*, and Shunsuke Chiba*. Chem. Commun. 2018, 54, 7535–7538

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Gold-catalyzed synthesis of β-trifluoromethylated α,β-unsaturated ketones from CF3-substituted propargylic carboxylates and their reactivity in Diels-Alder reactions


Invited article as part of a special issue in honor of Sir Derek Barton

Arnaud Boreux, Aubin Lambion, Dominic Campeau, Marina Sanita, Ruben Coronel, Olivier Riant*, and Fabien Gagosz*. Tetrahedron 2018, 74, 5232–5239

2017

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Acyl Fluorides as Efficient Electrophiles for the Copper-Catalyzed Boroacylation of Allenes

Arnaud Boreux, Kiran Inkuduri, Fabien Gagosz*, and Olivier Riant*. ACS Catal. 2017, 7, 8200–8204

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Synthesis of Allenamides and Structurally Related Compounds by a Gold-Catalyzed Hydride Shift Process


Selected as a very important paper

Qing Zhao* and Fabien Gagosz*. Adv. Synth. Catal. 2017, 359, 3108–3113

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Anti-Markovnikov Hydrofunctionalization of Alkenes - Use of a Benzyl Group as a Redox-Active Hydrogen Donor

Geoffroy Hervé Lonca, Derek Yiren Ong, Thi Mai Huong Tran, Ciputra Tejo, Shunsuke Chiba*, and Fabien Gagosz*. Angew. Chem. Int. Ed. 2017, 56, 11440–11444

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Gold(I)-catalyzed 6-endo-dig azide-yne cyclization: efficient access to 2H-1,3-oxazines

Geoffroy Hervé Lonca, Ciputra Tejo, Hui Ling Chan, Shunsuke Chiba*, and Fabien Gagosz*. Chem. Commun. 2017, 53, 736–739

2016

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Synthesis of Trifluoromethyl-allenes by Gold-Catalyzed Rearrangement of Propargyl Benzyl Ethers

Arnaud Boreux, Geoffroy Hervé Lonca, Olivier Riant*, and Fabien Gagosz*. Org. Lett. 2016, 18, 5162–5165

2014

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Divergent Product Selectivity in Gold- versus Silver-Catalyzed Reactions of 2-propynyloxy-6-fluoropyridines with Arylamines

Colombe Gronnier, Søren Kramer, and Fabien Gagosz*. Org. Lett. 2014, 16, 2092–2095

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Gold-Catalyzed Synthesis of Functionalized Pyridines Using 2H-Azirines As Synthetic Equivalents of Alkenyl Nitrenes


Selected as a “hot paper”

Agnes Prechter, Guilhem Henrion, Pierre Faudot dit Bel, and Fabien Gagosz*. Angew. Chem. Int. Ed. 2014, 53, 4959–4963

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Recent Progress towards Transition Metal-Catalyzed Synthesis of γ-Lactams

Long-Wu Ye*, Chao Shu, and Fabien Gagosz*. Org. Biomol. Chem. 2014, 12, 1833–1845

2013

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Photoredox Transformations with Dimeric Gold Complexes

Guillaume Revol, Terry McCallum, Mathieu Morin, Fabien Gagosz*, and Louis Barriault*. Angew. Chem. Int. Ed. 2013, 52, 13342–13345

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Au-Catalyzed Formation of Functionalized Quinolines from 2-Alkynyl Arylazide Derivatives

Colombe Gronnier, Guillaume Boissonnat, and Fabien Gagosz*. Org. Lett. 2013, 15, 4234–4237

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Gold-Catalyzed Tandem Cycloisomerization/Cope Rearrangement: An Efficient Access to the Hydroazulenic Motif

Ziping Cao and Fabien Gagosz*. Angew. Chem. Int. Ed. 2013, 52, 9014–9018

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Synthesis of Functionalized Chromenes and Benzofurans from Aryloxy Propargyl Malonates


Invited article as part of the special issue: “Homogeneous Gold Catalysis”

Igor Dias Jurberg, Keichi Ikeda, Dorothy Antwi-Omane, and Fabien Gagosz*. Isr. J. Chem. 2013, 53, 915–922

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New Biarylphosphonite Gold(I) Complexes As Superior Catalysts for the Oxidative Cyclization of Propynyl Arenes into Indan-2-ones

Guilhem Henrion, Thomas E. J. Chavas, Xavier Le Goff, and Fabien Gagosz*. Angew. Chem. Int. Ed. 2013, 52, 6277–6282

2012

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Cu(I)-Catalyzed Oxidative Cyclization of Alkynyl Oxiranes and Oxetanes

Colombe Gronnier, Soren Kramer, Yann Odabachian, and Fabien Gagosz*. J. Am. Chem. Soc. 2012, 134, 828–831

2011

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Gold-Catalyzed Transformation of 2-Alkynyl Arylazides: Efficient Access to the Valuable Pseudoindoxyl and Indolyl Frameworks


Selected as a “hot paper” and highlighted in the journal Synfacts (Issue 10, 2011)

Alexander Wetzel and Fabien Gagosz*. Angew. Chem. Int. Ed. 2011, 50, 7354–7358

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Gold and Brønsted Acid Catalyzed Hydride Shift onto Allenes: Divergence in Product Selectivity


Highlighted in Synfacts (Issue 8, 2011)

Benoit Bolte and Fabien Gagosz*. J. Am. Chem. Soc. 2011, 133, 7696–7699

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Gold(I)-catalyzed formation of furans by a Claisen-type rearrangement of ynenyl allyl ethers


Invited article as part of the special issue: “Gold catalysis for synthesis”

Florin M. Istrate and Fabien Gagosz*. Beilstein J. Org. Chem. 2011, 7, 878–885

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Taking Advantage of the Ambivalent Reactivity of Ynamides in Gold Catalysis: A Rare Case of Alkyne Dimerization

Søren Kramer, Yann Odabachian, Jacob Overgaard, Mario Rottländer, Fabien Gagosz*, and Troels Skrydstrup*. Angew. Chem. Int. Ed 2011, 50, 5090–5094

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Gold(I)-catalyzed formation of dihydroquinolines and indoles from N-aminophenyl propargyl malonates


Invited article as part of the thematic issue: “Emerging investigators”

Colombe Gronnier, Yann Odabachian, and Fabien Gagosz*. Chem. Commun. 2011, 47, 218–220

2010

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Hydroalkylation of Alkynyl ethers via a Gold(I)-Catalyzed 1,5-Hydride Shift/Cyclization Sequence

Igor Dias-Jurberg, Yann Odabachian, and Fabien Gagosz*. J. Am. Chem. Soc. 2010, 132, 3543–3548

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Formation of cinnoline derivatives by a gold(I)-catalyzed hydroarylation of N-propargyl-N’-arylhydrazines


Invited article as part of the special issue: “Catalytic addition of E-H bonds to non-activated C-C bonds”

Igor Dias-Jurberg and Fabien Gagosz*. J. Organomet. Chem. 2010, 696, 37–41

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Unusual Approach to Branched 3-Alkynylamides and to 1,5-Dihydropyrrol-2-ones

Igor Dias-Jurberg, Fabien Gagosz, and Samir Z. Zard*. Org. Lett. 2010, 12, 416–419

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La Catalyse à l’or: Un Outil Synthétique en Devenir

Fabien Gagosz. Actualité Chimique 2010, 347, 12–19

2009

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Cationic Dimetallic Gold Hydride Complex Stabilized by a Xantphos-Phosphole ligand: Synthesis, X-ray Crystal Structure, and Density Functional Theory Study

Aurélie Escalle, Guilhem Mora, Fabien Gagosz, Nicolas Mézailles, Xavier.-F. Le Goff, Yves Jean*, and Pascal Le Floch*. Inorg. Chem. 2009, 48, 8415–8422

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An Unusual Access to Medium Sized Cycloalkynes by a New Gold(I)-Catalyzed Cycloisomerization of Diynes

Yann Odabachian, Xavier –F. Le Goff, and Fabien Gagosz*. Chem. Eur. J. 2009, 15, 8966–8970

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Gold(I)-catalyzed [4+2] cycloaddition of N-(hex-5-enynyl) tert-butyloxycarbamates


Invited article as part of the special issue: “Gold Catalysis: New Perspectives for Homogeneous Catalysis

Andrea K. Buzas, Florin M. Istrate, Xavier-F. Le Goff, Yann Odabachian, and Fabien Gagosz*. J. Organomet. Chem. 2009, 694, 515–519

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Cyclobutenes as Isolable Intermediates in the Gold(I)-Catalysed Cycloisomerisation of 1,8-Enynes

Yann Odabachian and Fabien Gagosz*. Adv. Synth. Catal. 2009, 351, 379–386

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Gold-catalyzed rearrangement of propargylic tert-butyl carbonates

Andrea K. Buzas, Florin M. Istrate, and Fabien Gagosz*. Tetrahedron 2009, 65, 1889–1901

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Recent developments in gold catalysis


Invited as a guest editor for the special issue: “Recent Developments in Gold Catalysis”

Fabien Gagosz. Tetrahedron 2009, 65, 1757

2008

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Gold(I)-Catalyzed [4+2] Annelation/Nucleophilic Addition Sequence: Stereoselective Synthesis of Functionalized Bicyclo[4.3.0]nonenes


Invited as a guest editor for the special issue: “Gold Catalysis”

Sebastian Böhringer and Fabien Gagosz*. Adv. Synth. Catal. 2008, 350, 2617–2630

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Synthesis of Functionalized Oxazolones by a Sequence of Cu(II)- and Au(I)-Catalyzed Transformations

Florin M. Istrate, Andrea K. Buzas, Igor Dias-Jurberg, Yann Odabachian and Fabien Gagosz*. Org. Lett. 2008, 10, 925–928

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Amidyls in radical cascades. The total synthesis of (±)-aspidospermidine and (±)-13-deoxoserratine

Anne-Claude Caillet-Dublanchet, Jérôme Cassayre, Fabien Gagosz, Béatrice Quiclet-Sire, Lisa Sharp, and Samir Z. Zard*. Tetrahedron 2008, 64, 4803–4811

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Synthesis of Functionalized Furans via Gold (I)-Catalyzed Claisen-Type Rearrangement

Florin M. Istrate and Fabien Gagosz*. J. Org. Chem. 2008, 73, 730–733

2007

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Synthesis of Functionalized Pyrroles via Gold(I)-Catalyzed aza-Claisen Type Rearrangement

Florin M. Istrate and Fabien Gagosz*. Org. Lett. 2007, 9, 3181–3184

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Gold(I)-Catalyzed Isomerization of Allenyl Carbinol Esters: An Efficient Access to Functionalized 1,3-Butadien-2-ol Esters

Andrea K. Buzas, Florin M. Istrate, and Fabien Gagosz*. Org. Lett. 2007, 9, 985–988

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Gold(I)-Catalyzed 5-endo Hydroxy- and Alkoxycyclization of 1,5-enynes: Efficient Access to Functionalized Cyclopentenes

Andrea K. Buzas, Florin M. Istrate, and Fabien Gagosz*. Angew. Chem. Int. Ed. 2007, 46, 1141–1144

2006

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Gold(I)-Catalyzed Formation of 5-Methylene-1,3-oxazolidin-2-ones

Andrea K. Buzas and Fabien Gagosz*. Synlett 2006, 17, 2727–2730

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Gold(I) Catalyzed Stereoselective Formation of Functionalized 2,5-Dihydrofurans

Andrea K. Buzas, Florin M. Istrate, and Fabien Gagosz*. Org. Lett. 2006, 8, 1957–1959

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Gold(I)-Catalyzed Formation of 4-Alkylidene-1,3-dioxolan-2-ones from Propargylic tert-Butyl Carbonates

Andrea K. Buzas and Fabien Gagosz*. Org. Lett. 2006, 8, 515–518

2005

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Dibenzoyl peroxide

T. V. (Babu) RajanBabu and Fabien Gagosz. Dibenzoyl peroxide. e-EROS Encyclopedia of Reagents for Organic Synthesis; John Wiley & Sons, Ltd.: 2005; DOI: 10.1002/047084289X.rd022.pub2

PRIOR TO INDEPENDENT CAREER

2004

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The radical chemistry of xanthates: A powerful tool

Fabien Gagosz. Speciality Chemicals Magazine 2004, 10, 50–55

2003

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A Direct Approach to α-Trifluoromethyl Amines

Fabien Gagosz and Samir Z. Zard*. Org. Lett. 2003, 5, 2655–2657

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A Practical Radical Based Access to Functionalised Geminal Bisphosphonates

Fabien Gagosz and Samir Z. Zard*. Synlett 2003, 3, 387–389

2002

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Tin-free Radical Sequences under Acidic Conditions. Convergent Access to Azole-Containing Structures

Fabien Gagosz and Samir Z. Zard*. Org. Lett. 2002, 4, 4345–4348

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A New Tin-Free Source of Amidyl Radicals

Fabien Gagosz, Cécile Moutrille, and Samir Z. Zard*. Org. Lett. 2002, 4, 2707–2709

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A Short Synthesis of (±)-13-Deoxyserratine

Jérôme Cassayrre, Fabien Gagosz, and Samir Z. Zard*. Angew. Chem. Int. Ed. 2002, 41, 1783–1785

1999

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Generation and Capture of Iminyl Radicals from Ketoxime Xanthates

Fabien Gagosz* and Samir Z. Zard*. Synlett 1999, 12, 1978–1980

BOOK CHAPTERS

2017

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NHC–Copper, –Silver and –Gold Complexes in Catalysis

Arnaud Boreux, Nicolas Marion, and Fabien Gagosz*. Chapter 11: NHC–Copper, –Silver and –Gold Complexes in Catalysis. N-Heterocyclic Carbenes: From Laboratory Curiosities to Efficient Synthetic Tools: Edition 2; The Royal Society of Chemistry: 2017; pp 421–455

Editor: Silvia Diez-González

2015

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Gold-promoted sigmatropic rearrangements

Guilhem Henrion and Fabien Gagosz*. Gold-promoted sigmatropic rearrangements. The Chemistry of Organogold Compounds, 2 Volume Set - Patai's Chemistry of Functional Groups Series; John Wiley & Sons, Ltd.: 2015; pp 149–234

Editors: Zvi Rappoport, Joel F. Liebman, Ilan Marek, and Saul Patai

2014

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From Gold in Nature to Gold Catalysts

Søren Kramer and Fabien Gagosz*. Chapter 1: From Gold in Nature to Gold Catalysts. Gold Catalysis: An Homogeneous Approach - Catalytic Science Series: Volume 13; Imperial College Press, World Scientific Publishing Co. Pte. Ltd.: 2014; pp 1–49

Editors: F. Dean Toste, Véronique Michelet, and Graham J. Hutchings

2013

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Organogold Catalysis: Homogeneous Gold-catalyzed Transformations for a Golden Jubilee

Fabien Gagosz. Part II: Organometallic Synthesis and Catalysis, Chapter 16: Organogold Catalysis: Homogeneous Gold-catalyzed Transformations for a Golden Jubilee. Advances in Organometallic Chemistry and Catalysis: The Silver/Gold Jubilee International Conference on Organometallic Chemistry Celebratory Book; John Wiley & Sons, Ltd.: 2013; pp 207–225

Editor: Armando J. L. Pombeiro

2012

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Golden Opportunities in the Synthesis of Natural Products and Biologically Active Compounds

Fabien Gagosz. Chapter 4: Golden Opportunities in the Synthesis of Natural Products and Biologically Active Compounds. Modern Tools for the Synthesis of Complex Bioactive Molecules; John Wiley & Sons, Ltd.: 2012; pp 111–154

Editors: Janine Cossy and Stellios Arseniyadis